EGFR-IN-52 (Compound 4) is a highly effective inhibitor of the epidermal growth factor receptor (EGFR) with IC50 values of 0.358, 86.02, and 432.67 µM against EGFR, EGFR L858R-TK, and EGFR T790M-TK, respectively. Additionally, it demonstrates potent cytotoxic effects on cancer cell lines and triggers apoptosis [1].
Molekulargewicht:
382.44
CAS Nummer:
[454436-75-0]
Formel:
C19H18N4O3S
Target-Kategorie:
EGFR|||Apoptosis|||Others
T61646
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