TrxR-IN-5 (compound 4f) is an effective inhibitor of thioredoxin reductase (TrxR) with an IC50 of 0.16 µM. TrxR-IN-5 increases reactive oxygen species (ROS) levels, reverses TGFbeta1-induced epithelial-mesenchymal transition, and exhibits anti-proliferative and anti-metastatic effects against human breast cancer cells.
Molekulargewicht:
382.46
Formel:
C26H22O3
Target-Kategorie:
Others|||ROS
T61647
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
