mEH-IN-1 (Compound 62) is a potent inhibitor of microsomal epoxide hydrolase (mEH), with an IC50 value of 2.2 nM. This alpha/beta-fold hydrolase enzyme is widely expressed in mammalian tissues and primarily localized in the endoplasmic reticulum (ER) of eukaryotic cells, responsible for hydrolyzing various epoxide-containing molecules. Research on mEH-IN-1 can enhance the understanding of preeclampsia, hypercholanemia, and cancer [1].
Molekulargewicht:
385.37
CAS Nummer:
[2418576-06-2]
Formel:
C16H17F6NOS
Target-Kategorie:
Others|||Epoxide Hydrolase
T61690
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