Topoisomerase I inhibitor 4 (compound 7a) is a potent inhibitor of topoisomerase I activity, effectively inhibiting the proliferation of various cancer cell lines, including HepG2, A549, MCF-7, and HeLa, with IC50 values of 1.20 µM, 2.09 µM, 1.56 µM, and 1.92 µM, respectively. Thus, Topoisomerase I inhibitor 4 holds promise for cancer research applications [1].
Molekulargewicht:
386.42
CAS Nummer:
[2485135-31-5]
Formel:
C23H19FN4O
Target-Kategorie:
Others|||Topoisomerase
T61717
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