HDAC6/8/BRPF1-IN-1 is a dual inhibitor targeting HDAC6, HDAC8, and the bromodomain and PHD finger containing protein 1 (BRPF1). It exhibits inhibitory activity against HDAC1, HDAC6, and HDAC8 with IC50 values of 797 nM, 344 nM, and 908 nM, respectively, and inhibits BRPF1 with a Kd value of 175.2 nM. This compound is utilized in cancer research [1].
Molekulargewicht:
387.41
CAS Nummer:
[2484255-65-2]
Formel:
C18H17N3O5S
Target-Kategorie:
HDAC|||Others
T61727
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