OTS964 is a potent, orally active compound that operates as a highly selective inhibitor of TOPK with an IC 50 of 28 nM [1]. Additionally, it demonstrates significant inhibitory action against cyclin-dependent kinase CDK11, specifically binding to CDK11B with a K d of 40 nM [2].
Molekulargewicht:
392.51
CAS Nummer:
[1338542-14-5]
Formel:
C23H24N2O2S
Target-Kategorie:
Others|||TOPK|||CDK|||Apoptosis
T61800
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