DFBTA is a highly effective and orally active inhibitor of ANO1, specifically the calcium-activated chloride channel anoctamin-1. It exhibits potent inhibitory activity, with an IC 50 of 24 nM. Notably, DFBTA demonstrates significant analgesic efficacy in treating inflammatory pain [1].
Molekulargewicht:
393.79
Formel:
C18H10ClF2NO3S
Target-Kategorie:
Others|||Chloride channel
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