DNA-PK-IN-8 is a potent, selective, and orally active inhibitor of DNA-dependent protein kinase (DNA-PK) with an IC50 value of 0.8 nM, demonstrating synergistic antiproliferative effects across various cancer cell lines and significantly reducing HL-60 tumor growth when combined with Doxorubicin [1].
Molekulargewicht:
394.43
CAS Nummer:
[2823369-81-7]
Formel:
C19H22N8O2
Target-Kategorie:
DNA-PK|||Others
T61828
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