MAO-B-IN-10 (compound 4f) is a highly potent and selective MAO-B (monoamine oxidase-B) inhibitor that effectively penetrates the blood-brain barrier, exhibiting an IC50 of 5.3 µM. It demonstrates the ability to inhibit self-mediated Abeta (amyloid beta) aggregation by 58.2% and disaggregate it by 43.3%, holding promise for Alzheimers disease research [1].
Molekulargewicht:
394.46
Formel:
C23H26N2O4
Target-Kategorie:
Others|||Monoamine Oxidase|||Beta Amyloid
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