hCAIX-IN-8 (compound 7i) is a highly potent and selective inhibitor of hCAIX with an IC50 value of 0.024 µM, and also inhibits CAII and CAVA with IC50 values of 1.99 µM and 1.10 µM, respectively. It exhibits anti-proliferative effects, low toxicity, reduces epithelial-to-mesenchymal transitions, promotes apoptosis, and inhibits cell migration and colonization potential [1].
Molekulargewicht:
396.35
CAS Nummer:
[2414633-40-0]
Formel:
C19H16N4O6
Target-Kategorie:
Others|||Carbonic Anhydrase
T61852
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