Yhhu-3792 activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 enhanced the self-renewal ability of neural stem cells (NSCs), expanded the NSC pool and promoted endogenous neurogenesis in the dentate gyrus (DG) of the hippocampus in mice. Yhhu-3792 can improve the situational and spatial memory ability of mice. Yhhu-3792 has research potential in DG dysfunction related to memory impairment.
Molekulargewicht:
400.47
CAS Nummer:
[2097826-24-7]
Formel:
C24H24N4O2
Target-Kategorie:
Others|||Gamma-secretase
T61930
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