HGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). HGGPPS-IN-1 has an effective inhibitory effect on human geranyl geranyl pyrophosphate synthase (hGGPPS). HGGPPS-IN-1 can selectively induce apoptosis of multiple myeloma (MM) cells. HGGPPS-IN-1 showed anti-myeloma activity in vivo.
Molekulargewicht:
401.27
CAS Nummer:
[1429012-38-3]
Formel:
C13H13N3O6P2S
Target-Kategorie:
Others|||Apoptosis
T61945
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