LDN-209929 dihydrochloride is a potent and selective haspin kinase inhibitor with an IC50 value of 55 nM and approximately 180-fold selectivity over DYRK2 (IC50 = 9.9 µM), LDN-209929 represents an optimized analogue of LDN-192960 that is applied in cell cycle and mitotic regulation research to investigate haspin-dependent phosphorylation events.
Molekulargewicht:
405.77
CAS Nummer:
[1784281-97-5]
Formel:
C17H19Cl3N2OS
Target-Kategorie:
Haspin Kinase
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