NF-kappaB-IN-5 (compound 4d) is an orally active NF-kappaB inhibitor that interacts directly with NF-kappaB, and exhibits antitumor activity against human cancer cell lines, with IC50 values of 5.35, 2.81, 2.83, 2.02, and 3.90 µM for HCT116, U87-MG, HepG2, BGC823, and PC9, respectively.
Molekulargewicht:
409.48
CAS Nummer:
[2425675-52-9]
Formel:
C23H27N3O4
Target-Kategorie:
Others|||Apoptosis|||NF-kappaB
T62060
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