MAO-B-IN-7 is a potent and blood-brain barrier permeable MAO-B and AChE inhibitor, exhibiting IC50 values of 41 nM for human AChE, 87 nM for electric eel AChE, and 0.3 µM for MAO-B. MAO-B-IN-7 effectively alleviates oxidative stress and neuroinflammatory damage.