alpha7 nAchR-JAK2-STAT3 agonist 1, CAS [[2108714-20-9]]

Produktübersicht

• Artikelname: alpha7 nAchR-JAK2-STAT3 agonist 1, CAS [[2108714-20-9]]
• Artikelnummer: TGM-T62317
• Hersteller Artikelnummer: T62317
• Alternativnummer: TGM-T62317-25MG,TGM-T62317-50MG,TGM-T62317-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

alpha7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the alpha7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 µM). It has demonstrated positive effects on iNOS, IL-1beta, and IL-1beta in murine macrophages RAW264.7, and inhibited the expression of iNOS, IL-1beta, and IL-6 in mouse macrophages. Additionally, alpha7 nAchR-JAK2-STAT3 agonist 1 suppressed LPS-induced NO release, NF-kappaB activation, and cytokine production, making it useful for studying sepsis.

Produkteigenschaften

• Molekulargewicht: 426.5
• CAS Nummer: [2108714-20-9]
• Formel: C25H30O6
• Target-Kategorie: JAK|||STAT|||AChR|||Others|||NO Synthase

Bilder

T62317