Branaplam hydrochloride, CAS [[1562338-39-9]]

Produktübersicht

• Artikelname: Branaplam hydrochloride, CAS [[1562338-39-9]]
• Artikelnummer: TGM-T62381
• Hersteller Artikelnummer: T62381
• Alternativnummer: TGM-T62381-1MLX10MM(INDMSO),TGM-T62381-1MG,TGM-T62381-5MG,TGM-T62381-10MG,TGM-T62381-25MG,TGM-T62381-50MG,TGM-T62381-100MG,TGM-T62381-200MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: NVS-SM1 hydrochloride , LMI 070 hydrochloride , LMI070 hydrochloride

Produktbeschreibung

Branaplam hydrochloride (LMI070, NVS-SM1) is a selective and orally active SMN2 splicing modulator that acts directly on SMN with an EC50 value of 20 nM. Branaplam hydrochloride also inhibits hERG channels, demonstrating an IC50 of 6.3 µM. In a mouse model of severe spinal muscular atrophy (SMA), Branaplam hydrochloride significantly increased full-length SMN protein levels and markedly improved survival.

Produkteigenschaften

• Molekulargewicht: 429.95
• Reinheit: 98.45%
• CAS Nummer: [1562338-39-9]
• Formel: C22H28ClN5O2
• Target-Kategorie: Others|||Potassium Channel|||DNA/RNA Synthesis

Bilder

T62381

T62381