Cathepsin C-IN-5 (compound SF38) is a potent, selective, and orally active Cathepsin C inhibitor with an IC50 of 59.9 nM for Cat C, and significantly lower potency against Cat L (4.26 µM), Cat S, Cat B, and Cat K (all >5 µM). It reduces Cat C activity in bone marrow and blood, diminishes NSPs activation, and exhibits anti-inflammatory activity [1].
Molekulargewicht:
436.92
CAS Nummer:
[2825567-97-1]
Formel:
C21H17ClN6OS
Target-Kategorie:
Others|||Cysteine Protease
T62494
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