(R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that disrupts superhelical activity (IC50: 875 µM) and exhibits antibacterial activity against Pseudomonas aeruginosa E. coli with MIC values of 10-80 µM, without affecting the closely related enzyme topoisomerase IV.
Molekulargewicht:
442.97
CAS Nummer:
[1793050-70-0]
Formel:
C21H28ClFN2O3S
Target-Kategorie:
Antibacterial|||Others
T62592
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