NSD2-IN-1 (compound 38) is a potent and highly selective inhibitor of NSD2-PWWP1 (nuclear receptor-binding SET domain 2-PWWP1), with an IC50 value of 0.11 µM. By binding to NSD2-PWWP1, NSD2-IN-1 influences gene expression regulated by NSD2, resulting in apoptosis and cell cycle arrest [1].
Molekulargewicht:
449.59
CAS Nummer:
[2797183-37-8]
Formel:
C29H31N5
Target-Kategorie:
Others|||Apoptosis
T62705
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