RTI-7470-44 is a potent and selective human trace amine-associated receptor 1 (hTAAR1) antagonist (IC50: 8.4 nM) that crosses the blood-brain barrier. RTI-7470-44 increases the spontaneous firing rate of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain in mice. RTI-7470-44 can be used to study schizophrenia, drug addiction and Parkinsons disease (PD).
Molekulargewicht:
449.84
CAS Nummer:
[825658-63-7]
Formel:
C19H11ClF3N5OS
Target-Kategorie:
Others
T62706
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