LY487379 is a selective human mGluR2 positive allosteric modulator (PAM) that enhances glutamate-stimulated [35 S] GTPgammaS binding to mGlu2 receptors (EC50: 1.7 µM) and mGlu3 receptors (EC50 >10 µM). LY487379 induces cognitive flexibility and behavioral inhibition in a rat model and can be used to study schizophrenia.
Molekulargewicht:
452.45
Reinheit:
99.94%
CAS Nummer:
[353231-17-1]
Formel:
C21H19F3N2O4S
Target-Kategorie:
Others|||GluR
T62756
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