TPB15 is an orally active inhibitor of Hh (Hedgehog) signalling. TPB15 significantly blocks the MDA-MB-468 cell cycle and induces apoptosis. TPB15 blocks Smo (Smoothened) translocation into cilia and reduces Smo protein and mRNA expression. TPB15 has good anti-tumour effects and low toxicity.
Molekulargewicht:
453.11
CAS Nummer:
[2170347-69-8]
Formel:
C18H9Cl4N5O
Target-Kategorie:
Apoptosis|||Others|||Hedgehog/Smoothened|||Smo
T62772
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten