AMXI-5001 is a potent, orally active inhibitor of PARP1/2 and microtubule aggregation. AMXI-5001 shows selective anti-tumor cytotoxicity against a wide range of human cancer cells with IC50s well below those of existing clinical PARP1/2 inhibitors and induces complete regression of established tumors, including very large ones.
Molekulargewicht:
457.46
CAS Nummer:
[2170491-77-5]
Formel:
C25H20FN5O3
Target-Kategorie:
Microtubule Associated|||Others
T62847
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