YM-341619 (AS1617612) is a potent, orally active STAT6 inhibitor (IC50: 0.70 nM) that inhibits IL-4-induced Th2 differentiation in mouse splenic T cells with an IC50 value of 0.28 nM, without affecting Th1 cell differentiation. YM-341619 holds potential for research into allergic diseases, such as allergic asthma.
Molekulargewicht:
458.44
CAS Nummer:
[643082-52-4]
Formel:
C22H21F3N6O2
Target-Kategorie:
Others|||STAT
T62860
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