Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (alpha, beta1, beta2, theta), exhibiting inhibitory activity on AurA (IC50: 6.9 nM) and PKCalpha (IC50: 16.9 nM), and demonstrating anti-proliferative and anti-metastatic effects on breast cancer cells.
Molekulargewicht:
464.24
CAS Nummer:
[2143100-98-3]
Formel:
C16H14N6OSe2
Target-Kategorie:
Others|||PKC|||Aurora Kinase
T62945
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