Rucaparib (AG014699) tartrate is an orally active inhibitor of PARP proteins (PARP-1, PARP-2, and PARP-3) and acts on PARP-1 (Ki: 1.4 nM). It is also a hexose hexaphosphate dehydrogenase (H6PD) inhibitor and has potential for use in the study of destructive resistant prostate cancer (CRPC).
Molekulargewicht:
473.457
CAS Nummer:
[773059-22-6]
Formel:
C23H24FN3O7
Target-Kategorie:
Others|||PARP
T63065
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