Chitin synthase inhibitor 12, a Chitin synthase (CHS) inhibitor, showed excellent CHS inhibition (IC50: 0.16 mM). Chitin synthase inhibitor 12 is also a broad-spectrum antifungal agent resistant to resistant fungal variants (e.g. C. albicans, C. neoformans). Chitin synthase inhibitor 12 can be used to study invasive fungal infections (IFIs).
Molekulargewicht:
473.88
Formel:
C23H21ClFN3O5
Target-Kategorie:
Others|||Antifungal
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