Simmiparib (SMOCL-9112) is a novel and potent PARP1 and PARP2 inhibitor, a derivative of Olaparib.Simmiparib induces DNA double-strand breaks (DSBs) and cell cycle arrest in homologous recombination repair (HR)-deficient cells, thereby contributing to apoptosis.Simmiparib has been used for study Parkinsons disease, Alzheimers disease, breast cancer, and melanoma.
Molekulargewicht:
486.42
Reinheit:
99.51%
CAS Nummer:
[1551355-46-4]
Formel:
C23H18F4N6O2
Target-Kategorie:
Apoptosis|||PARP
T63228
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