Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1, and IP, with values of 3.6, 4.4, and 32.1 nM for EP2, DP1, and IP, respectively, and 212, 826, 2505, and 4680 nM for EP1, EP4, EP3, and FPKi, respectively. Treprostinil diethanolamine contributes to the upregulation of cAMP, maintaining vascular homeostasis and causing vasodilation in human pulmonary arteries.
Molekulargewicht:
495.65
Reinheit:
98.21%
CAS Nummer:
[830354-48-8]
Formel:
C27H45NO7
Target-Kategorie:
Prostaglandin Receptor
T63349
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