Top/HDAC-IN-1
Artikelnummer:
TGM-T63509
| Artikelname: |
Top/HDAC-IN-1 |
| Artikelnummer: |
TGM-T63509 |
| Hersteller Artikelnummer: |
T63509 |
| Alternativnummer: |
TGM-T63509-25MG,TGM-T63509-50MG,TGM-T63509-100MG |
| Hersteller: |
TargetMol |
| Kategorie: |
Biochemikalien |
| Top/HDAC-IN-1 is a dual topoisomerase (Top)/HDAC inhibitor that acts on HDAC1 (IC50: 18 nM), HDAC2 (IC50: 230 nM), HDAC3 (IC50: 790 nM), HDAC6 (IC50: 87 nM) and HDAC8 (IC50: 5250 nM). Top/HDAC-IN-1 exhibited potent antitumor effects on HCT116 cells (IC50: 180 nM), blocked the cell cycle of HCT116 cells in G2 phase, and effectively induced apoptosis. |
| Molekulargewicht: |
509.56 |
| Formel: |
C29H27N5O4 |
| Target-Kategorie: |
Others|||Apoptosis|||Topoisomerase|||HDAC |
