XPO1-IN-1 is an orally active XPO1 inhibitor capable of acting on MM.1S cells (IC50: 24 nM). XPO1-IN-1 effectively induces cell cycle arrest and apoptosis. XPO1-IN-1 exhibits good metabolic stability and pharmacokinetic properties. XPO1-IN-1 can be used to study multiple myeloma.
Molekulargewicht:
519.42
Formel:
C20H15F6N5O3S
Target-Kategorie:
Others|||Apoptosis
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