KRAS G12C inhibitor 47 is a potent inhibitor of KRAS G12C (IC50: 0.172 µM). KRAS G12C inhibitor 47 exhibits p-ERK inhibition in MIA PaCA-2 cells, A549 cells with IC50 values of 0.046 µM and 69.8 µM respectively. KRAS G12C inhibitor 47 showed investigational potential against pancreatic, colorectal and lung cancers.
Molekulargewicht:
547.02
CAS Nummer:
[2253119-24-1]
Formel:
C30H28ClFN4O3
Target-Kategorie:
Ras|||Others|||Kras
T63863
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