MU1656 is a potent and selective inhibitor of histone methyltransferase DOT1L (IC50 = 2 nM), a key epigenetic regulatory protein involved in the development of cancers such as hematologic malignancies, thus MU1656 was able to significantly inhibit the proliferation of cancer cells and induce apoptosis.
Molekulargewicht:
559.75
Reinheit:
96.92%
CAS Nummer:
[2766698-38-6]
Formel:
C32H45N7O2
Target-Kategorie:
Histone Methyltransferase
T63955
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