PI3K-IN-29, a potent inhibitor of PI3K, exhibits substantial inhibition capabilities against U87MG, HeLa, and HL60 cells, with IC50 values of 0.264, 2.04, and 1.14 µM, respectively. It effectively blocks the PI3K/Akt signaling pathway by preventing the PI3K-catalyzed phosphorylation of Akt [1].
Molekulargewicht:
560.03
CAS Nummer:
[2768005-77-0]
Formel:
C27H22ClN7O3S
Target-Kategorie:
Others|||Akt|||PI3K
T63957
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