Keap1-Nrf2-IN-14 is a KEAP1-NRF2 inhibitor that effectively disrupts the KEAP1-NRF2 interaction (IC50: 75 nM) with a Kd=24 nM for KEAP1. Keap1-Nrf2-IN-14 induces the expression of NRF2 target genes and is able to enhance downstream antioxidant and anti-inflammatory effects. -Nrf2-IN-14 can be used to study oxidative stress-related inflammation.
Molekulargewicht:
563.62
CAS Nummer:
[1928782-31-3]
Formel:
C30H29NO8S
Target-Kategorie:
Reactive Oxygen Species|||Others|||Nrf2
T63987
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