FGFR4-IN-6 is a covalent, reversible FGFR4 inhibitor (IC50: 5.4 nM) that exhibits good oral pharmacokinetic properties. In a xenograft mouse model of the Hep3B2.1-7 HCC cell line, FGFR4-IN-6 was able to significantly induce tumour regression without significant toxicity.
Molekulargewicht:
567.64
Formel:
C31H33N7O4
Target-Kategorie:
Others|||FGFR
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
