BPN-15606 besylate is a potent, orally active gamma-secretase regulator (GSM) that reduces the production of Abeta42 (IC50: 7 nM) and Abeta40 (IC50: 17 nM) by SHSY5Y neuroblastoma cells. BPN-15606 besylate exhibited good PK/PD properties (including bioavailability, half-life and clearance).
Molekulargewicht:
576.64
Formel:
C29H29FN6O4S
Target-Kategorie:
Others|||Gamma-secretase
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