TCMDC-135051 TFA is a potent, highly selective, low off-target toxicity protein kinase PfCLK3 inhibitor that exhibits antiparasitic effects with an EC50 value of 320 nM. TCMDC-135051 TFA blocks the trophozoite to lytic transition, disrupts transcription and inhibits transmission to mosquito vectors.
Molekulargewicht:
585.61
Formel:
C31H34F3N3O5
Target-Kategorie:
Others|||Parasite
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