Rucaparib (AG014699) camsylate is an orally active inhibitor of PARP proteins (PARP-1, PARP-2, and PARP-3) with a Ki=1.4 nM for PARP-1, and also inhibits hexose hexaphosphate dehydrogenase (H6PD). Rucaparib camsylate has potential for investigation in debulking resistant prostate cancer (CRPC) studies.
CAS Nummer:
[1327258-57-0]
Formel:
C19H18FN3O.xC10H16O4S
Target-Kategorie:
Others|||PARP
T64289
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