TDI-10229 is a potent and orally available inhibitor of soluble adenylyl cyclase (sAC, ADCY10), displaying nanomolar inhibition of sAC in both biochemical and cellular assays (IC50 = 195 nM). TDI-10229 exhibits mouse pharmacokinetic properties sufficient to warrant its use as an in vivo tool compound.
Molekulargewicht:
313.78
Reinheit:
99.89%
CAS Nummer:
[2810887-45-5]
Formel:
C16H16ClN5
Target-Kategorie:
AChR|||cAMP
T64355
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