PCSK9-IN-11 (compound 5r) is a potent PCSK9 inhibitor with oral activity, exhibiting inhibitory activity on PCSK9 transcription in HepG2 cells (IC50 = 5.7 µM) and capable of increasing LDL receptor (LDLR) protein levels. PCSK9-IN-11 is applicable for atherosclerosis research.
Molekulargewicht:
381.789
Reinheit:
99.10%
CAS Nummer:
[2882035-56-3]
Formel:
C16H17ClFN5O3
Target-Kategorie:
Others|||LDLR
T67776
T67776
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