all-trans-Retinoic acid-d5 , Vitamin A acid-d5 , ATRA-d5 , Accutane-d5
Retinoic acid-d5 (Vitamin A acid-d5) is the deuterium-labeled form of Retinoic acid. Retinoic acid is a natural RAR receptor agonist with an IC50 of 14 nM for RARalpha/beta/gamma and a Kd of 17 nM for PPARbeta/delta. Retinoic acid, a metabolite of vitamin A, plays an important role in cell growth, differentiation and organ development. Retinoic acid acts by activating retinoic acid receptor alpha as an inhibitor of the transcription factor Nrf2.