Fc 11a-2, a benzimidazole compound, functions as an orally active, potent inhibitor of the NLRP3 inflammasome by blocking caspase-1 activation and thus preventing the activation of IL-1beta/IL-18. Additionally, Fc 11a-2 inhibits the progression of Dextran sulfate sodium (DSS)-induced murine experimental colitis [1] [2] [3].
Molekulargewicht:
236.31
CAS Nummer:
[960119-75-9]
Formel:
C16H16N2
Target-Kategorie:
NOD-like Receptor (NLR)|||Others
T68225
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