AF3442, CAS [[924636-93-1]]

Produktübersicht

• Artikelname: AF3442, CAS [[924636-93-1]]
• Artikelnummer: TGM-T68334
• Hersteller Artikelnummer: T68334
• Alternativnummer: TGM-T68334-25MG,TGM-T68334-50MG,TGM-T68334-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

AF3442 is a potent and selective mPGES-1 inhibitor (microsomal prostaglandin (PG) E synthase-1). AF3442 caused a concentration-dependent inhibition of PGE(2) in human recombinant mPGES-1 with an IC(50) of 0.06microM. AF3442 is a selective mPGES-1 inhibitor which reduced monocyte PGE(2) generation also in the presence of plasma proteins. Pharmacological inhibition of mPGES-1 did not translate into redirection of PGH(2) metabolism towards other terminal PG synthases in monocytes. The functional relevance of this observation deserves to be investigated in vivo.

Produkteigenschaften

• Molekulargewicht: 382.38
• CAS Nummer: [924636-93-1]
• Formel: C22H17F3N2O
• Target-Kategorie: Others

Bilder

T68334