Rolapitant hydrochloride hydrate, CAS [[914462-92-3]]

Produktübersicht

• Artikelname: Rolapitant hydrochloride hydrate, CAS [[914462-92-3]]
• Artikelnummer: TGM-T68371
• Hersteller Artikelnummer: T68371
• Alternativnummer: TGM-T68371-25MG,TGM-T68371-50MG,TGM-T68371-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). This may prevent both SP-induced emesis and chemotherapy-induced nausea and vomiting (CINV). The interaction of SP with the NK1-receptor plays a key role in the induction of nausea and vomiting caused by emetogenic cancer chemotherapy.

Produkteigenschaften

• Molekulargewicht: 554.95
• CAS Nummer: [914462-92-3]
• Formel: C25H29ClF6N2O3
• Target-Kategorie: Others|||Neurokinin receptor

Bilder

T68371