A-849519 is a reversible inhibitor of MetAP2 that has demonstrated anti-angiogenesis and anticancer activity in a number of in vitro and in vivo models. In this study, we evaluated the anticancer activity of A-849519 in a modified Dunning model of androgen-independent prostate cancer and compared its efficacy with TNP-470, an established MetAP2 inhibitor.
Molekulargewicht:
432.51
CAS Nummer:
[904680-01-9]
Formel:
C22H25FN2O4S
Target-Kategorie:
Others
T68406
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