ZK-Thiazolidinone, CAS [[891849-87-9]]

Produktübersicht

• Artikelname: ZK-Thiazolidinone, CAS [[891849-87-9]]
• Artikelnummer: TGM-T68428
• Hersteller Artikelnummer: T68428
• Alternativnummer: TGM-T68428-25MG,TGM-T68428-50MG,TGM-T68428-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

ZK-Thiazolidinone, also known as TAL, is an ATP-competitive inhibitor of PLK1. In vitro, ZK-Thiazolidinone counteracts the role of Plk1 in previously established functions, notably, sister chromatid separation, centrosome maturation, and bipolar spindle assembly. In vivo, ZK-Thiazolidinone selectively inhibits PLK1 and causes a prometaphase-like mitotic (G2-M) arrest. ZK-Thiazolidinone inhibits human PLK1 (IC50, 19 12 nM) and various human and mouse tumor cell lines (IC50, 0.2-1.3 µM). ZK-Thiazolidinone impairs centrosome maturation.

Produkteigenschaften

• Molekulargewicht: 493.55
• CAS Nummer: [891849-87-9]
• Formel: C23H26F3N5O2S
• Target-Kategorie: Others

Bilder

T68428