WAY-255348, CAS [[872141-23-6]]

Artikelnummer: TGM-T68473
Artikelname: WAY-255348, CAS [[872141-23-6]]
Artikelnummer: TGM-T68473
Hersteller Artikelnummer: T68473
Alternativnummer: TGM-T68473-25MG,TGM-T68473-50MG,TGM-T68473-100MG
Hersteller: TargetMol
Kategorie: Biochemikalien
WAY-255348 is a potent nonsteroidal progesterone receptor (PR) antagonist. WAY-255348 inhibits the activity of progesterone. WAY-255348 achieves antagonist activity by binding to and subsequently preventing progesterone-induced nuclear accumulation, phosphorylation and promoter interactions of the PR. WAY-255348 bound PR conformation was similar to that of a progesterone agonist-bound PR and distinct from steroidal antagonist-bound PR conformations. WAY-255348 inhibits PR action through a novel molecular mechanism that is distinct from previously studied PR modulators and may be a useful tool to further understanding of PR signaling pathways.
Molekulargewicht: 283.3
CAS Nummer: [872141-23-6]
Formel: C16H14FN3O
Target-Kategorie: Others
T68473