Totrombopag, also known LGD-4665, GSK2285921 and SB559448, is an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. It is a highly selective and potent agonist of the TPO receptor and therefore induces differentiation and proliferation of megakaryocytes. The pharmacologic characteristics indicate potential therapeutic use in thrombocytopenic patients with a variety of clinical etiologies.
Molekulargewicht:
569.67
CAS Nummer:
[851606-62-7]
Formel:
C30H35N9O3
Target-Kategorie:
Others|||Thrombopoietin Receptor
T68560
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